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Lactones

mycotrienolI

(81904-15-6)

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Dicirenone

(41020-79-5)
Hypotensive; aldosterone antagonist.

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Rutamycin

(1404-59-7)
Oligomycin D (rutamycin) is macrocyclic lactone belonging to the oligomycin class but identified from different species of Streptomyces in 1961. Like oligomycin A, oligomycin D inhibits mitochondrial F1F0-ATPase and is an important bioprobe to study the organisation of ATPase on the mitochondrial membrane. Oligomycin D exhibits a broad biological profile including antifungal, antitumor and nematocidal activities.

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Lactone refers to an organic substance that contains both a carboxyl group and a hydroxyl group in the same molecule, and the two are dehydrated. Organic compounds with one and only one ester group in the ring. Common ones are x=2, 3 or 4, which are called β-, γ- or δ-lactones, respectively. They are generally insoluble in water, easily soluble in organic solvents such as ethanol and ether, and their density is generally lower than that of water.
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