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Home > Active Pharmaceutical Ingredients > Nervous System Drugs (Find 4 items)

2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1)

(138982-67-9)
Ziprasidone is the hydrochloride salt of a benzisothiazolylpiperazine analog structurally related to the atypical antipsychotic drug tiospirone that antagonizes both central serotonin 5-HT2A (Ki = 0.42 nM) and dopamine D2 (Ki = 4.8 nM) receptors. It is also a potent agonist at 5-HT1A receptors (Ki = 3.4 nM), increasing cortical dopamine release which may offset negative effects associated with dopamine D2 antagonism, and an inverse agonist at 5-HT1B and 5-HT1D receptors (pKis = 8.8 and 8.6, resp

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2,4,5-Trimethoxyamphetamine

(1083-09-6)
TMA-2, known more formally as 2,4,5-trimethoxy-amphetamine, is a psychedelic hallucinogen which has appeared on the illicit drug market. Unlike amphetamines and cathinones, TMA-2 has no effect on monoamine re-uptake. TMA has modest effects on the 5-HT2 serotonin receptors (pEC50 values of 5.15 and 5.31 M for phosphatidylinositol release through 5-HT2A and 5HT2C, respectively). This product is intended for research and forensic applications.[Cayman Chemical]

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Nervous system drugs mainly include: sedative and hypnotic, antiepileptic and anticonvulsant, anxiolytics, antipsychotics, antidepressants, antimanics drugs, antiparkinson drugs, drug Metabolism in human brain, cholinergic drugs, central stimulant drugs, parkinson's disease drugs and other nervous system drugs. "ECHEMI The Nervous System Drugs "list mainly supplies APIs for such drugs.
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