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Home > Active Pharmaceutical Ingredients > Nervous System Drugs (Find 345 items)

Doxepin

(1668-19-5)
Used clinically to treat anxiety and depression. Antidepressant

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Azacyclonol

(115-46-8)
α-(4-Piperidyl)benzhydrol is a key intermediate in the synthesis of Fexofenadine (F322490).

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Clomipramine hydrochloride

(17321-77-6)
Serotonin reuptake inhibitor. Antidepressant; antiobsessional agent

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2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1)

(138982-67-9)
Ziprasidone is the hydrochloride salt of a benzisothiazolylpiperazine analog structurally related to the atypical antipsychotic drug tiospirone that antagonizes both central serotonin 5-HT2A (Ki = 0.42 nM) and dopamine D2 (Ki = 4.8 nM) receptors. It is also a potent agonist at 5-HT1A receptors (Ki = 3.4 nM), increasing cortical dopamine release which may offset negative effects associated with dopamine D2 antagonism, and an inverse agonist at 5-HT1B and 5-HT1D receptors (pKis = 8.8 and 8.6, resp

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(+)-Bromocriptine

(25614-03-3)
This product has the excitatory effect of dopamine receptors. It can penetrate the blood-brain barrier and enter the central nervous system, excite dopamine receptors and inhibit the secretion of prolactin and growth hormone. Clinically used for Parkinson~"s disease, acromegaly and galactorrhea.

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Coluracetam

(135463-81-9)
Coluracetam(MKC-231) is a new choline uptake enhancer.IC50 value:Target:in vitro: MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding [1].in vivo: Oral administration of MKC-231 (1-10 mg/kg) significant

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Acetylcholine

(51-84-3)
neurotransmitter (ester of choline and acetic acid)

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Asenapine

(65576-45-6)
Combined serotonin (5HT2) and dopamine (D2) receptor antagonist; structurally related to Mianserin. Antipsychotic

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Nervous system drugs mainly include: sedative and hypnotic, antiepileptic and anticonvulsant, anxiolytics, antipsychotics, antidepressants, antimanics drugs, antiparkinson drugs, drug Metabolism in human brain, cholinergic drugs, central stimulant drugs, parkinson's disease drugs and other nervous system drugs. "ECHEMI The Nervous System Drugs "list mainly supplies APIs for such drugs.
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