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Related News
Nitro Compounds
Nitro Compounds
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Pimonidazole
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Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor. Pimonidazole is used for intravenous administration followed by biopsy, it can be used for qualitative and quantitative assessment of tumor hypoxia[1].Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group[2].
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Nitro compounds can be divided into R-NO2 and Ar-NO2 according to different hydroxyl groups. Nitro compounds can be used as chemical raw materials and organic synthesis reagents in medicine, dyes, spices, explosives and other industries. Polynitro compounds are unstable, have strong oxidizing power, and can be used as explosives. Liquid compounds of nitro have certain chemical stability, so they are often used as solvents for some organic reactions.
