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Home > Organic Chemistry > Nitrogen Compounds (Find 14 items)

Nitrogen Compounds

3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone

(491871-58-0)
TCS PIM-1 1(sc-204330) is a potent and selective ATP-competitive Pim-1 kianse inhibitor with IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2(IC50s >20,000 nM).IC50 value: 50 nM [1]Target: Pim-1TCS PIM-1 1 bound convincingly within the ATP-binding site of Pim-1 suggesting an ATP-competitive inhibitory mechanism. Preliminary data further suggested that 1 lacked in vitro inhibitory activity toward related serine/threonine kinases Pim-2 and MEK1/2 (IC50 > 20 lM). Hence, sma

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Organic Nitrogen Compounds generally refer to organic compounds containing carbon-nitrogen bonds in the molecule, including amines, nitrogen heterocycles, nitriles, nitro compounds and the like. Organic nitrogen-containing compounds are widespread in nature and are a very important class of compounds. Many organic nitrogen-containing compounds have biological activities, such as alkaloids; some are indispensable substances for life activities, such as amino acids; many drugs and dyes are also organic nitrogen compounds.

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