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Home > Biochemical Engineering > Nucleoside Drugs (Find 69 items)

Nucleoside Drugs

2′-O-Methyluridine

(2140-76-3)
Uridine analog. Used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replication.

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2-Fluoroadenosine

(146-78-1)
Used as intermediate of drug fludarabine

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2′-Deoxy-2′-fluorocytidine

(10212-20-1)
2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine has been shown to inhibit Borna Disease virus replication and spread.

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2'-C-Methyluridine

(31448-54-1)
A 2’C-Me branched C-nucleoside that shows HCV polymerase inhibitory activity.

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2'-Deoxyadenosine monohydrate

(16373-93-6)
Used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents.

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Nucleoside drugs are an important class of drugs used clinically to treat viral infectious diseases, tumors, and AIDS. Nearly 50% of the currently used antiviral drugs are nucleoside drugs, and the antitumor drugs Cytarabine, Doxifluridine, etc. also belong to the nucleoside class. Nucleoside and deoxynucleoside series derivatives have a variety of biologically active substances, which can be used directly or indirectly as drugs, and play an extremely important role in the treatment of a variety of major diseases.
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