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Home > Biochemical Engineering > Nucleoside Drugs (Find 69 items)

Nucleoside Drugs

2′,3′-Isopropylideneguanosine

(362-76-5)
A useful precursor for the preparation of nucleic acids

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2-IODOADENOSINE

(35109-88-7)
An intermediate in the synthesis of isoguanosine (crotonoside or 2-hydroxyadenosine), a naturally occuring nucleoside analogue of guanosine.Isoguanosine is incorporated into mammalian but not bacterial nucleic acids, stimulates the accumulation of cyclic AMP in the brain, and is an inhibitor of IMP:pyrophosphorylase.

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2′-Azido-2′-deoxyuridine

(26929-65-7)
2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity[1].

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2'-C-Methylcytidine

(20724-73-6)
NM107 is a inhibitors of HCV RNA replication with IC50 of 7.0 μM in vitro.IC50 value: 7.0 μMTarget:HCV RNA replicationNM107 is a potent and selective inhibitor of flavi- and pesti-virus replication in cell culture, with inhibitory activity and cytotoxicity against HCV 1b replicon cells, IC50 is 1.13 μM. Intracellular HCV RNA in HCV-infected cells treated the HCV polymerase inhibitor NM107 shows a similar pattern of decline. NM107 are currently being investigated as additional therapeutic

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2′,3′-O-(1-Methylethylidene)inosine

(2140-11-6)
An inosine derivative as antiviral, bactericidal, and antitumor agent for immunopotentiating uses.

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Nucleoside drugs are an important class of drugs used clinically to treat viral infectious diseases, tumors, and AIDS. Nearly 50% of the currently used antiviral drugs are nucleoside drugs, and the antitumor drugs Cytarabine, Doxifluridine, etc. also belong to the nucleoside class. Nucleoside and deoxynucleoside series derivatives have a variety of biologically active substances, which can be used directly or indirectly as drugs, and play an extremely important role in the treatment of a variety of major diseases.
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