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Home > Biochemical Engineering > Nucleoside Drugs (Find 52 items)

Nucleoside Drugs

5-Fluorouracil

(51-21-8)
5-Fluoro Uracil is an active metabolite of Doxifluridine(D556750).

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5-Aza-2′-deoxycytidine

(2353-33-5)
Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively

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5-Methyluridine

(1463-10-1)
A primary degradation product of tRNA,

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5-Fluorocytidine

(2341-22-2)
5-Fluoropyrimidine nucleotides as probes of RNA structure using 19F-NMR spectroscopy

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5-Chlorouracil

(1820-81-1)
Used for the experimental and clinical treatment of neoplastic and viral diseases

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5-Fluorouridine

(77180-80-4)
Intermediates, genetic engineering and biochemical reagents used in the production of anti-tumor drugs DFUR and FUDR, etc.

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Nucleoside drugs are an important class of drugs used clinically to treat viral infectious diseases, tumors, and AIDS. Nearly 50% of the currently used antiviral drugs are nucleoside drugs, and the antitumor drugs Cytarabine, Doxifluridine, etc. also belong to the nucleoside class. Nucleoside and deoxynucleoside series derivatives have a variety of biologically active substances, which can be used directly or indirectly as drugs, and play an extremely important role in the treatment of a variety of major diseases.
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