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Home > Biochemical Engineering > Nucleoside Drugs (Find 24 items)

Nucleoside Drugs

6-Azathymine

(932-53-6)
ChEBI: A nucleobase analogue that is thymine in which the CH group at position 6 is replaced by nitrogen.

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6-Thioxanthine

(2002-59-7)
A metabolite of6-Mercaptopurine (M225450).

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6-Methylthioguanine

(1198-47-6)
A metabolite of 2’-Deoxy-6-thio Guanosine (D281650) and 6-Thioguanine. An effective immunosuppressant and anticancer agent, however chronic exposure can be mutagenic in human cells as long-term use of thiopurines was found to be associated with a significantly increased risk of various types of cancer.

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Nucleoside drugs are an important class of drugs used clinically to treat viral infectious diseases, tumors, and AIDS. Nearly 50% of the currently used antiviral drugs are nucleoside drugs, and the antitumor drugs Cytarabine, Doxifluridine, etc. also belong to the nucleoside class. Nucleoside and deoxynucleoside series derivatives have a variety of biologically active substances, which can be used directly or indirectly as drugs, and play an extremely important role in the treatment of a variety of major diseases.
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