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Home > Biochemical Engineering > Nucleoside Drugs (Find 346 items)

Nucleoside Drugs

3H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine

(1123-54-2)
off-white powderChEBI: A triazolopyrimidine that is [1,2,3]triazolo[4,5-d]pyrimidine bearing an amino substituent at position 7.

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Adenosine 5′-(trihydrogen diphosphate), sodium salt (1:2)

(16178-48-6)
Adenosine 5~"-diphosphate (ADP) is an adenine nucleotide that is converted into ATP by ATP synthase, thereby participating in energy storage and nucleic acid metabolism. ADP affects platelet activation by interacting with ADP receptors P2Y1, P2Y12 and P2X1. When it is catalyzed by ecto-ADP enzyme to adenosine, platelet activation is inhibited by adenosine receptors.

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5-Methylcytosine

(554-01-8)
5-Methylcytosine is a well-characterized DNA modification, and is also predominantly in abundant non-coding RNAs in both prokaryotes and eukaryotes. 5-Methylcytosine in mRNA is a new epitranscriptome marker inArabidopsis, and that regulation of this modification is an integral part of gene regulatory networks underlying plant development[1].

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dATP

(1927-31-7)
It is used as a substrate for DNA polymerases, reverse transcriptases

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6-Methylmercaptopurine

(50-66-8)
Metabolite of 6-Mercaptopurine, an immunosuppressive drug used to treat leukemia.

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Nucleoside drugs are an important class of drugs used clinically to treat viral infectious diseases, tumors, and AIDS. Nearly 50% of the currently used antiviral drugs are nucleoside drugs, and the antitumor drugs Cytarabine, Doxifluridine, etc. also belong to the nucleoside class. Nucleoside and deoxynucleoside series derivatives have a variety of biologically active substances, which can be used directly or indirectly as drugs, and play an extremely important role in the treatment of a variety of major diseases.
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