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Home > Biochemical Engineering > Polypeptide (Find 624 items)

Polypeptide

Polypeptides are vital biomolecules with broad applications in biology and industry. It is composed of amino acids linked by polypeptide bonds. These polypeptide chains form the backbone of most proteins and are key to cellular functions, enzyme regulation, and structural support. Their efficiency makes them valuable in biotechnology, medicine, and manufacturing. Learn more about polypeptides, including CAS No., properties, and information of materials and products from our suppliers on ECHEMI.

Ziconotide acetate

(107452-89-1)
Ligand for binding studies of voltage sensitive calcium channels.

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Terlipressin Acetate

(914453-96-6)
Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controlling acute variceal bleeding. Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock treatment[1][2][3][4][5].

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Felypressin

(56-59-7)
Felypressin(Octapressin) is a vasopressin 1 agonist and a peptide containing eight amino acids including cystine. Felypressin is used as a vasoconstrictor.

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SERUM THYMIC FACTOR

(63958-90-7)
Applicable to primary and secondary immunodeficiency diseases, diseases caused by immune dysfunction, adjuvant treatment of tumors, aplastic anemia, acute and chronic viral hepatitis, but also for lupus erythematosus, rheumatoid arthritis, allergic asthma, etc. .

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ANGIOTENSINII,HUMAN

(4474-91-3)
Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two distinct receptors, AT1 and AT2, each evoking distinct signaling pathways and physiological responses. The development of antagonists for specific angiotensin II receptor subtypes repres

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Eledoisin

(69-25-0)
Eledoisin is a specific agonist of NK2 and NK3 receptors. Sequence: {Glp}-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2.

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Polypeptide is a compound formed by connecting α-amino acids with peptide bonds, and is an intermediate product of protein hydrolysis. Compounds usually formed by the dehydration and condensation of 10 to 100 amino acid molecules are called peptides. There are two types of peptides: biologically active peptides and synthetic peptides.

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Application of polypeptide

With recent advancements in biotechnology, polypeptides have found increasing use as therapeutic agents. They can serve in diagnostic, curative, and preventative applications and can be synthesized artificially to meet clinical demands.

Due to their unique properties, polypeptides combine the characteristics of both small molecule drugs and protein-based therapies, making them a highly researched class of molecules. Insulin, for example, was the first polypeptide drug introduced, and since then, over 80 polypeptide-based drugs have been commercialized. These include peptide vaccines, anti-cancer peptides, antiviral peptides, cardiovascular peptides, cytokine mimetic peptides, antimicrobial peptides, and diagnostic peptides.

One of the major advantages of polypeptide drugs is their reduced likelihood of inducing drug resistance. However, they also pose significant challenges, such as higher toxicity and lower stability compared to other drug types. The immunogenicity and instability of polypeptide drugs are often attributed to chemical reactions like deamidation, oxidation, hydrolysis, and the formation of incorrect structures.

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