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Sesquiterpene

Sesquiterpenes are compounds built of three isoprene units and demonstrate a high variety of structures and functions. The sesquiterpene lactones with lactone rings are endowed with biological activities. Monoterpenes and sesquiterpenes are important in the synthesis of fragrances, flavors and pharmaceuticals because of their versatility. Read about Sesquiterpene, including CAS No., properties and information on materials and products of suppliers on ECHEMI.

Tussilagone

(104012-37-5)
Tussilagone, a major active component in Tussilago farfara, has anti-inflammatory effect. Tussilagone ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis. Tussilagone inhibits the inflammatory response and improves survival in cecal ligation and puncture (CLP)-induced septic mice[1][2].

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Brevilin A

(16503-32-5)
This naturally occurring sesquiterpenoid (FW = 346.40 g/mol; CAS 16503- 32-5) from the volatile oils of the plant Centipeda minima inhibits (IC50 = 10 μg/mL) STAT3 phosphorylation in the Jak/STAT signal transduction pathway of A549R cells. Brevilin A showed high specificity on Janus Kinase activity and following STAT3 signaling without directly affecting some other signals, including p65, AKT and GSK-3β phosphorylation, as well as Src kinase activity. Brevilin A is also an antibiotic with activ

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Spathulenol

(6750-60-3)
Spathulenol is isolated from Psidium guineense Sw, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC50 of 85.60 μg/mL in the DPPH system[1].

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Deoxyartemisinin

(72826-63-2)
An analogue of Artemisinin, an antimalarial agent

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The sesquicarbonyl group (sesquiterpene) refers to a natural alkyl compound containing 15 carbon atoms in the molecule and contains three isoprene units. It has various stacking structures such as chain and ring. Uncle sesqui is mostly liquid and mainly exists in the volatile oil of plants. Oxygen derivatives such as alcohols, ketones and lactones are also widely present in volatile oils.

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Sesquiterpenes are natural organic compounds derived from three isoprene units; forming a major sub-group of the terpenes. Sesquiterpenes are highly structurally diverse and have important functional properties that find uses in numerous sectors. A particular subgroup, a sesquiterpene lactone, contains a lactone ring, which is a source of its wide spectrum of activity, including anti-inflammatory and antimicrobial action. This interlocking between monoterpenes and sesquiterpenes in essential oils further complements their fragrance and increases their market demand.

Sesquiterpenes obtained from natural resources such as plants and flowers have found their way into producing raw materials for high-level industries. These poorly defined compounds are not only useful for their bioactivities but also for their chemical tunability to drive new products.

Applications of Sesquiterpenes:

● Manufacturing of perfumes and olive oils.

● Synthesis of natural food and beverage flavoring.

● The synthesis of pharmaceutical compounds.

● Natural pesticides and repellents are manufactured.

● Improvement of the cosmetic goods.

● For the study of bioactive compounds.

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