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Analytical Chemistry

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N,N'-bis-(2-Chloroethyl)urea

(2214-72-4)
1,3-Bis(2-chloroethyl)urea is an impurity in the synthesis of Carmustine (C183875), an alkylating and carbamoylating nitrosourea compound.It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.

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Nicotyrine

(487-19-4)
Nicotryrine is an alkaloid derived from the dehydrogenation of nicotine and its analog, nornicotine. An alkaloid occurring in cigaret smoke.

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N′-Nitrosoanabasine

(1133-64-8)
The S-enantiomer metabolite of tobacco, a specific N-nitrosamines with carcinogenic activity.

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N,N′-Dipropylurea

(623-95-0)
Labelled N,N'-Dipropylurea (D492460). It is used in the synthesis of symmetrically N,N'-disubstituted aliphatic ureas as intermediates for antitumor drug

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N,N-Dimethylmelamine

(1985-46-2)
N-Demethylated metabolite of Altretamine (A575765) with antitumor activity. It is used as a chemosterilant for insects, particularly houseflies.

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Nitrosomorpholine

(59-89-2)
N-Nitrosomorpholine, a frequently used genotoxic model carcinogen. Toxicogenomic analysis of N-Nitrosomorpholine induced changes in rat liver.

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In the analysis work, it is often necessary to use a compound of good quality and accurate content, which is used as a comparison for detection control, or used to calibrate the instrument. This compound is called a standard. Or standard. The standard product refers to the standard substance used to determine the potency of biological products. The production department must provide the standard product expressed in units (μ) of its potency when it is approved as a quality standard for biological products. According to the application, the standard products for inspection can be divided into biological standard products for biological verification of biological products, endocrine drugs, antibiotics and so on.
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