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Analytical Chemistry

Standard

1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone

(92264-81-8)
A metabolite of Bupropion, an antidepressant.The compound exists mainly as cyclic acetal (2-hydroxy-2-(3?chlorophenyl)-355-trimethylmorpholine).See US Pat. # 6342496

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3-(1-Nitroso-2-pyrrolidinyl)pyridine

(80508-23-2)
N'-Nitrosonornicotine (NNN) is a tobacco alkaloid known as esophageal carcinogen. NNN is the cause of esophageal and oral cavity cancer in smokers and snuff dippers. The studies showedthat the carcinogenicity of (S)-NNN, the predominant enantiomer in tobacco products, may be greater than that of (R)-NNN or racemic NNN.

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Atorvastatin Related Compound A (20 mg) (Desfluoro impurity,or (3R,5R)-7-[3-(phenylcarbamoyl)-2-isopropyl-4,5-diphenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acidcalcium salt)

(433289-83-9)
Desfluoro Atorvastatin is an impurity in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

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Ticabesone Propionate

(73205-13-7)
Ticabesone Propionate is an impurity of Fluticasone, an antiallergic, anti-asthmatic and anti-inflammatory agent.

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L-Nateglinide

(105816-05-5)
An impurity found within the commercial pharmaceutical Nateglinide (N379375), a common antidiabetic

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2-(1-Methylethyl)pentanoic acid

(62391-99-5)
A constitutional isomer of Valproic acid; a potent anticonvulsant. Sodium valproate impurity C

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3-Amino-5-[[(2-hydroxyethyl)amino]carbonyl]-2,4,6-triiodobenzoic acid

(22871-58-5)
Intermediate in the preparation of Ioxitalamic Acid (I738100). An iodine-containing X-ray contrast agent.

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In the analysis work, it is often necessary to use a compound of good quality and accurate content, which is used as a comparison for detection control, or used to calibrate the instrument. This compound is called a standard. Or standard. The standard product refers to the standard substance used to determine the potency of biological products. The production department must provide the standard product expressed in units (μ) of its potency when it is approved as a quality standard for biological products. According to the application, the standard products for inspection can be divided into biological standard products for biological verification of biological products, endocrine drugs, antibiotics and so on.
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