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Home > Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs (Find 587 items)

Ofloxacin hydrochloride

(118120-51-7)
Fully synthetic antibiotics, used to treat diseases caused by various bacterial infections

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Rufloxacin

(101363-10-4)
A tricyclic fluoroquinolone formulated as the hydrochloride salt. It is inactive against Gram-positive cocci with MICs >2 mg/L. It displays weak activity in vitro against Enterobacteriaceae with the MIC for most species >1 mg/L. Activity against Ps. aeruginosa is poor (MIC 16–32 mg/L). After loading doses of 400 and 600 mg followed with 9 days of either 200 or 300 mg, mean peak plasma levels were around 4.5–7 mg/L, respectively. The mean apparent elimination halflife was 44 h. Approximately 50%

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Garenoxacin

(194804-75-6)
Des-F(6)-quinolone antibacterial; topoisomerase II inhibitor. Antibacterial.

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Orbifloxacin

(113617-63-3)
Orbifloxacin is a fluoroquinolone antibiotic used in veterinary medicine, mainly for the treatment of staphylococcal infections in dogs.

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Synthetic anti-infective drugs refer to a class of drugs (or chemotherapeutic drugs) that inhibit or kill pathogenic microorganisms. Anti-infective drugs are basic medications, and are widely used in the treatment of various infections such as bacterial infections, fungal infections, chlamydia infections, viral infections, and other complications caused by other diseases. Synthetic anti-infective drugs mainly include: sulfonamides and antibacterial synergists, quinolones, anti-tuberculosis drugs, antifungal drugs, antiviral drugs, antiparasitic drugs, etc. Synthetic antibacterial drugs mainly include sulfonamides and their synergists, quinolones and nitroimidazoles. The "ECHEMI Synthetic Anti-infective Drugs" list mainly supplies APIs for such drugs.
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