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Terpenes

Friedelin

(559-74-0)
Friedelin is isolated from isolated from the leaves of Maytenus ilicifolia(Mart). Friedelin is a noncompetitive inhibitor of CYP3A4 with IC50 and Kivalues of 10.79  μM and 6.16  μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1 with IC50 and Ki values of 22.54  μM and 18.02 μM, respectively[1].

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Terpenes are a class of hydrocarbons of natural origin widely found in plants and can be obtained from many plants, especially conifers. It is the main component of resin and turpentine derived from resin. The total number of currently known terpenoids exceeds 22,000. Many terpenoids have important physiological activities and are an important source for researching natural products and developing new drugs.
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