Thiamine chloride (Vitamin B1) - SNC | Good Fortune

Vitamin B1

Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,chloride (1:1);Thiamine;Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,chloride;3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride (1:1);3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride;Aneurine;Apatate Drape;Beivon;Bethiamin;Oryzanin;Vitamin B1;Thiamine monochloride;Thiamin;Vitaneurin;Thiacoat;3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride;3-((4-Amino-2-methylpyrimidin-5-yl)methyl)-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride;100660-17-1;115461-66-0;55463-15-5;57777-32-9

59-43-8

C12H17N4OS.Cl

InChIKey=MYVIATVLJGTBFV-UHFFFAOYSA-M

300.81

300.081

200-425-3

X66NSO3N35

DTXSID2023648

C874

Crystals from water

A11DA01|A - Alimentary tract and metabolism

3004500000

Vitamins and Minerals Medicines

104

-1.80710

Small white to yellowish crystals or crystalline powder

1.43 g/cm³

248 °C (decomp)

351.9°C at 760 mmHg

In water, approximately 5.0X10+5 mg/L, temp not specified

The drug is not highly susceptible to atmospheric oxidation but should be protected from air and light. Thiamine hydrochloride tablets should be stored in tight, light-resistant containers at a temperature less than 40 degrees C, preferably between 15-30 degrees C. Thiamine hydrochloride injection should be protected from light and stored at a temperature less than 40 degrees C, preferably between 15-30 degrees C; freezing should be avoided.

1.8X10-10 mm Hg at 25 deg C (est)

SLIGHT, CHARACTERISTIC

Monoclinic plates in rosette-like clusters. Slight thiazole odor; bitter taste; decomposes at 248 °C. One gram dissolves in approximately 1 mL water, 18 mL glycerol, 100 mL 95% alcohol, 315 mL absolute alcohol; more soluble in methanol. Soluble in propylene glycol. Practically insoluble in ether, benzene, hexane, chloroform. pH of 1% wt/vol solution in water 3.13; pH of 0.1% wt/vol solution in water 3.58. On exposure to air of average humidity, the vitamin absorbs an amount of water corresponding to nearly one mole, forming a hydrate.|HYGROSCOPIC; NUT-LIKE ODOR /HYDROCHLORIDE/|READILY SPLIT BY SULFITE INTO ITS PYRIMIDINE & THIAZOLE CONSTITUENTS|Crystals. MP: 196-200 °C, decomposes; practically nonhygroscopic; pKa = 4.9. Solubility in water (g/100 mL): 2.7 (25 °C); approximately 30 (100 °C). pH of 2% aqueous solution 6.5 to 7.1, more stable than the hydrochloride; suitable for enrichment of flours and feeds, multivitamin preparations /Mononitrate/|SMALL WHITE CRYSTALS OR CRYSTALLINE POWDER /HYDROCHLORIDE/|Thiamine hydrochloride in the dry state is stable. Acidic solutions having a pH below 5.5 preferably from 5.0 to 3.5 are also relatively stable. Alkalies destroy it. It is precipitated from solution by several of the alkaloidal reagents such as mercuric chloride, iodine, picric acid, tannin, and Mayer's reagent. It is sensitive to both oxidizing and reducing agents. /Hydrochloride/|For more Other Experimental Properties (Complete) data for Vitamin B1 (6 total), please visit the HSDB record page.