 Home > Encyclopedia > Loracarbef

Loracarbef

Loracarbef structure

CAS No:
76470-66-1
Formula:
C16H16ClN3O4
Chemical Name:
Loracarbef
Synonyms:
1-Azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-,(6R,7S)-;1-Azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[(aminophenylacetyl)amino]-3-chloro-8-oxo-,[6R-[6α,7β(R*)]]-;1-Azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-aminophenylacetyl]amino]-3-chloro-8-oxo-,(6R,7S)-;(6R,7S)-7-[[(2R)-2-Amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;LY 163892;Loracarbef;KT 3777;Loribid;Lorabid;Loracarbacef
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Loracarbef (Lorabid), a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class[1][2].

Loracarbef Basic Attributes

Molecular Weight：

367.78

Exact Mass：

349.77

Characteristics

PSA：

112.73000

XLogP3：

1.73990

Density：

1.52g/cm3

Melting Point：

205-215 °C

Boiling Point：

662.2ºC at 760 mmHg

Flash Point：

354.3ºC

Refractive Index：

1.677

Water Solubility：

3.25e-01 g/L

Loracarbef Use and Manufacturing

An antibiotic, a synthetic carbacephem analogue of cefaclor, and is more stable chemically.