 Home > Encyclopedia > Isoconazole nitrate

Isoconazole nitrate

Isoconazole nitrate structure

CAS No:
24168-96-5
Formula:
C18H14Cl4N2O.HNO3
Chemical Name:
Isoconazole nitrate
Synonyms:
1H-Imidazole,1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-,nitrate (1:1);Imidazole,1-[2,4-dichloro-β-[(2,6-dichlorobenzyl)oxy]phenethyl]-,mononitrate;1H-Imidazole,1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-,mononitrate;Isoconazole nitrate;Adestan G 100;Gyno-Travogen;Fazol;Travogen;R 15454;Travogyn
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Isoconazole nitrate is a broad-spectrum antimicrobial agent with a highly effective antimycotic and gram-positive antibacterial activity, a rapid rate of absorption and low systemic exposure potential. Isoconazole nitrate is effective against pathogens involved in dermatomycoses, with minimum inhibitory concentrations well below the concentration of ISN in skin and hair follicles.

Isoconazole nitrate Basic Attributes

Molecular Weight：

479.14

Exact Mass：

476.981659

EC Number：

246-051-4

HScode：

2933290090

Characteristics

PSA：

93.1

XLogP3：

6.63030

Appearance：

White crystals or crystalline powder

Density：

1.4 g/cm3

Melting Point：

182-183 °C

Boiling Point：

555.1ºC at 760 mmHg

Flash Point：

289.5ºC

Storage Conditions：

Refrigerator

Safety Information

RTECS Number：

NI4772000

Precautionary statement(s)：

P273, P391, P501

Hazard Statements：

H400

GHS Classification：

|Warning|H400 (94.44%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]|P273, P391, and P501|Aggregated GHS information provided by 37 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)

MeSH Entry Terms：

1-(2,4-dichloro beta-(2,6-dichlorobenzyloxy)phenethyl) imidazole

Isoconazole nitrate Use and Manufacturing

Antibacterial; antifungal

Computed Properties

Molecular Weight:479.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:478.978717
Monoisotopic Mass:476.981667
Topological Polar Surface Area:93.1
Heavy Atom Count:29
Complexity:431
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Recommended Suppliers of Isoconazole nitrate

Hangzhou KieRay Chem Co. Contact Supplier

CN
4 YRS

Business licensed Certified factory

Manufactory Supplier of fine chemicals,pharmaceutical materials

Isoconazole nitrate

CAS No.: 24168-96-5

Grade: industrial Grade

Content: 98%

Inquiry
henan kanbei chemical co.,ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of 1H,1H,2H,2H-PERFLUORODECYLTRIMETHOXYSILANE

high purity hot sale Isoconazole Nitrate 99% high quality see COA KANBEI

CAS No.: 24168-96-5

Grade: Industrial Grade

Content: 99%

Inquiry

41 Suppliers of Isoconazole nitrate