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BEAUVERICIN

BEAUVERICIN structure

BEAUVERICIN 

structure
  • CAS No:

    26048-05-5

  • Formula:

    C45H57N3O9

  • Chemical Name:

    BEAUVERICIN

  • Synonyms:

    Beauvericin, froM Beauveria bassiana;CYCLO-[D-ALPHA-HYDROXYISOVALERYL-L-N-METHYLPHENYLALANYL]3;CYCLO(-D-ALPHA-HYDROXYISOVALERYL-N-ME-PHE)3;BEAUVERICIN;cyclo(d-α-hydroxyisovaleryl-l-n-methyl-phe)3;BEAUVERFICIN;beauverin;beauverin bassiaua vuillemin

  • Categories:

    Biochemical Engineering  >  Polypeptide

Description

Beauvericin is a Fusarium mycotoxin. Beauvericin inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 3 μM in an enzyme assay using rat liver microsomes[1].

BEAUVERICIN Basic Attributes

783.95

783.409485

708472

29419090

Characteristics

139.83000

5.49

1.1±0.1 g/cm3

93-94℃

975.6±65.0 °C at 760 mmHg

543.8±34.3 °C

1.530

2-8°C

0mmHg at 25°C

Safety Information

NONH for all modes of transport

3

Drug Information

beauvericin

BEAUVERICIN Use and Manufacturing

Methods of Manufacturing

Production process of Beauveria bassiana: Slant culture[28℃]→Supplement bottle expansion culture[28℃]→Seed tank culture[28℃]→Reproduction tank culture[28℃]→Ferment tank culture[CaCO3, filler]→ Spray drying→The nutritional requirements of Beauveria bassiana products are mainly carbon and nitrogen sources, and a small amount of trace elements. According to its aerobic characteristics, it is necessary to select raw materials with loose texture and high sugar content to prepare the culture medium, such as rice bran skin, bran, soybean cake, glucose, potassium dihydrogen phosphate, etc. Beauveria bassiana can grow and reproduce at 5~30℃, with 24~28℃ being the most suitable. Controlling the proper temperature and humidity can also prevent the growth of mixed bacteria.

Uses

Toxic depsipeptide with antibiotic and insecticidal effects.

Computed Properties

Molecular Weight:783.9
XLogP3:8.4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:9
Exact Mass:783.40948040
Monoisotopic Mass:783.40948040
Topological Polar Surface Area:140
Heavy Atom Count:57
Complexity:1200
Undefined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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