NEUROPEPTIDE FF
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NEUROPEPTIDE FF
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CAS No:
99566-27-5
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Formula:
C54H76N14O10
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Chemical Name:
NEUROPEPTIDE FF
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Synonyms:
PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE AMIDE;PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2;NPFF;NEUROPEPTIDE FF;H-PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2;F-8-F-NH2;ninamide;phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylala
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CAS No:
Description
Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation[1][2].
Drug Information
Agents inhibiting the effect of narcotics on the central nervous system. (See all compounds classified as Narcotic Antagonists.)
F-8-F-amide
Computed Properties
Molecular Weight:1081.3
XLogP3:-0.3
Hydrogen Bond Donor Count:12
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:32
Exact Mass:1080.58688468
Monoisotopic Mass:1080.58688468
Topological Polar Surface Area:415
Heavy Atom Count:78
Complexity:2050
Defined Atom Stereocenter Count:6
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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