2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE
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2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE
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CAS No:
19225-92-4
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Formula:
C5H7ClN2
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Chemical Name:
2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE
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Synonyms:
2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE;AKOS BBS-00005326;1-Methyl-2-(chloromethyl)imidazole;2-(Chloromethyl)-N-methylimidazole;2-Chloromethyl-1-methylimidazole;2-(ChloroMethyl)-1-Methyl-1H-iMidazole, >95%;1H-Imidazole,2-(chloromethyl)-1-methyl-
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CAS No:
Safety Information
IRRITANT
Xi
P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, P501
H314
|Danger|H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501|Aggregated GHS information provided by 3 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE Use and Manufacturing
To 1.12 g of 1-methyl-2-imidazolemethanol are added dropwise 1.8 ml of thionyl chloride at 0° C. ^-ChloromethyM-methyl-I H-imidazole] (14)To a solution of compound 13 (250 mg, 2.23 mmol) in chloroform (5 mL) was added thionyl chloride (500 mg, 4.20 mmol) and refluxed for 3 h. The reaction mixture was allowed to come to room temperature and concentrated. The reaction mixture was diluted with diethyl ether (30 mL) and concentrated. The crude product 14 (200 mg, 67percent) was characterized by GC-MS and it was used as such for the next step.
2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE
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