2-Chloro-3,5-dimethylpyrazine
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2-Chloro-3,5-dimethylpyrazine
structure -
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CAS No:
38557-72-1
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Formula:
C6H7ClN2
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Chemical Name:
2-Chloro-3,5-dimethylpyrazine
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Synonyms:
Pyrazine,2-chloro-3,5-dimethyl-;2-Chloro-3,5-dimethylpyrazine
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CAS No:
Safety Information
3
1993
36/38
23-26-36/37/39
Harmful
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501
H302
|Warning|H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2-Chloro-3,5-dimethylpyrazine Use and Manufacturing
Preparation of Cpd 88 HFirst, a synthesis method of an intermediate, 2-chloro-3, 5-dimethylpyrazine is described. 7.12 g of 2, 6-dimethylpyrazine and 6.5 mL of dimethylformamide (abbreviation : DMF) were put in a three-neck flask equiiped with a drop funnel and a thermometer, and the inside was refluxed under a nitrogen atmosphere. 6.7 mL of sulfuric chloride was put in a drop funnel and the reaction container was soaked in an ice bath. While the reaction solution was being stirred, the sulfuric chloride was dropped in such a way that the temperature of the solution be kept 45 °C +/- 5 °C. After that, water was added after it was confirmed that the temperature of the solution was 40
Computed Properties
Molecular Weight:142.58
XLogP3:1.5
Hydrogen Bond Acceptor Count:2
Exact Mass:142.0297759
Monoisotopic Mass:142.0297759
Topological Polar Surface Area:25.8
Heavy Atom Count:9
Complexity:97.1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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