Manganese carbonate

114.94700

114.92300

241-414-3

9ZV57512ZM

DTXSID1042108

Pink to almost white powder when freshly precipitated; rhombohedral, calcite structure|Rose-colored crystals, almost white when precipitated.|Pink solid trigonal

2836999000

63.19000

-2.44700

DryPowder; Liquid; OtherSolid; WetSolid

3.7 g/cm³

350ºC

333.6ºC at 760 mmHg

169.8ºC

soluble in dilute inorganic acids; almost insoluble in common organic acids, both concentrated and dilute.

Store in a cool, dry place. Keep container closed when not in use.

Heating above 200 °C causes decomposition to manganese oxide and carbon dioxide.

NONH for all modes of transport

3

S22-S24/25

OM2470000

Stable. Incompatible with strong acids, strong oxidizing agents. May be moisture senstive.

P201, P202, P260, P264, P270, P281, P307+P311, P308+P313, P314, P321, P405, P501

H360

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Trace minerals added to animal feeds. These substances added to animal feeds as nutritional dietary supplements are generally recognized as safe when added at levels consistent with good feeding practice. Element: Manganese; Source compound: manganese carbonate. (All substances listed may be in anhydrous or hydrated form.)

Not Classified| |Danger|H360: May damage fertility or the unborn child [Danger Reproductive toxicity]|P201, P202, P260, P264, P270, P281, P307+P311, P308+P313, P314, P321, P405, and P501|H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]|P260, P264, P270, P307+P311, P314, P321, P405, and P501

SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.

Permissible Exposure Limit: Table Z-1 Ceiling value: 5 mg/cu m. /Manganese cmpd (as Mn)/

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 1 mg/cu m. /Manganese compounds and fume (as Mn)/|Recommended Exposure Limit: 15 Min Short-Term Exposure Limit: 3 mg/cu m. /Manganese compounds and fume (as Mn)/

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Manganese carbonate is included on this list.|... Substances for which a Federal Register notice has been published that included consideration of the serious health effects, including cancer, form ambient air exposure to the substance. Manganese (50 FR 32627; Aug. 13, 1985) is included on this list. /Manganese/

Occurs in nature as the mineral rhodochrosite.

MANGANESE CARBONATE IS USED IN MEDICINE AS A HEMATINIC

The subcellular distribution of manganese (Mn) in brains of mice chronically admin Mn in different chemical forms with food was examined using gel chromatography. Male ddY-mice were divided into five groups of six animals each, & Groups 1 to 4 were given 2 grams/kilogram Mn of standard laboratory mouse chow) in the form of manganese chloride (MnCl2), manganese acetate (MnAc), manganese carbonate (MnCO3), or manganese oxide (MnO2), in the diets for 12 months, while Group 5 served as control. 24 hr after the last feed, animals were decapitated & brains were rapidly removed for study of the different regions (corpus striatum (CS), hypothalamus, midbrain, cerebral cortex (CC), hippocampus, cerebellum, & medulla oblongata). Subcellular fractions (mitochondrial, microsomal & cytosolic) & gel chromatography fractions were analyzed for Mn contents using flame atomizer absorption spectrophotometry. Results showed that CC levels of Mn in mice exposed to the nearly insoluble MnCO3 & MnO2 were higher than in controls, while Mn concns in the CS were similar to those in controls. Microsomal Mn in treated mice was also higher than in controls. The gel chromatographic profile of CS showed that 20% Mn was in the high molecular weight (MW) fractions, 45% was in the middle MW fractions, while 32% was in the low MW fractions. The % Mn in high MW fractions was higher (29% to 49%) in the Mn treated groups, than in controls. The % of Mn in low MW fractions of the MnO2 exposed group (9%) was lower than in the MnCl2, MnAc, & MnCO3 exposed groups (42%, 36%, & 38%, respectively). The authors conclude that the brain regional distribution of Mn from the virtually insoluble cmpds is different from that of soluble Mn cmpds, & that striatal subcellular & gel chromatographic profiles are similar for the divalent Mn cmpds. They add that there is more Mn associated with fast migrating ligands in the striatal cytosol of the Mn treated groups than in the controls, & that these binding characteristics are different from those of other organs.

IMPURITIES MAY BE CALCIUM OXIDE AND SODIUM OXIDE.

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . /Manganese and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in severe respiratory distress. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Manganese and related compounds/

manganese carbonate

Grades: chemical (46% manganese)|44% manganese; acid soluble.

Agriculture, forestry, fishing and hunting|Carbonic acid, manganese(2+) salt (1:1): ACTIVE|... /EXTRACTED FROM MINES/ WHERE MANGANESE CARBONATE /OCCURS/ IN QUARTZ & GRANITE ... /AS IN THE MINES AT BUTTE, MONTANA/. LARGE DEPOSITS CONTRIBUTING TO WORLD SUPPLY REQUIRE SIMPLE CONCENTRATING PROCESSES, SUCH AS WASHING TO REMOVE CLAY & PRIMARY CRUSHING. LOW GRADE ORES ARE BENEFICIATED BY SULFURIC ACID, SULFUR DIOXIDE LEACH, OR BY NITRIC OXIDE, NITRIC ACID LEACH.