(+)-Cucurbitacin B
-
(+)-Cucurbitacin B
structure -
-
CAS No:
6199-67-3
-
Formula:
C32H46O8
-
Chemical Name:
(+)-Cucurbitacin B
-
Synonyms:
19-Norlanosta-5,23-diene-3,11,22-trione,25-(acetyloxy)-2,16,20-trihydroxy-9-methyl-,(2β,9β,10α,16α,23E)-;19-Nor-9β,10α-lanosta-5,23-diene-3,11,22-trione,2β,16α,20,25-tetrahydroxy-9-methyl-,25-acetate;(2β,9β,10α,16α,23E)-25-(Acetyloxy)-2,16,20-trihydroxy-9-methyl-19-norlanosta-5,23-diene-3,11,22-trione;Cucurbitacin B;Cucurbitacine B;Amarine;NSC 144154;NSC 49451;(+)-Cucurbitacin B;HY-N 0416;120614-91-7;22076-50-2
- Categories:
-
CAS No:
Description
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids; could repress cancer cell progression.IC50 value:Target: anticancer natural compoundin vitro: Cucurbitacin-B inhibited growth and modulated expression of cell-cycle regulators in SHSY5Y cells. At the molecular level, we found that Cucurbitacin-B inhibited AKT signaling activation through up-regulation of PTEN [1]. CuB induced apoptosis of A549 cells in a -concentration-dependent manner, as determined by fluor
Characteristics
138
2.6
white to beige
1.2±0.1 g/cm3
184-186 °C
699.3±55.0°C at 760 mmHg
218.8±25.0 °C
1.568
DMSO: soluble 10mg/mL, clear
2-8°C
Oral-Mouse LD50: 14 mg/kg; Abdominal cavity-mouse LD50: 1 mg/kg
Flammable, spicy and irritating smoke emitted from the fire
D25 +88° (c = 1.55 in ethanol)
Safety Information
Ⅰ
6.1
UN 2811 6.1 / PGI
3
25
45-24/25
RC6190000
T
Treasury is low temperature, ventilated, dry; stored separately from food raw materials
P264; P301 + P310
H300
Learn More Other Chemicals
-
Picrasin B acetate
30315-04-9
-
Rifamycin B pyrrolidide
13929-40-3
-
Desogestrel EP IMpurity B
54024-12-3
-
BRADYKININ POTENTIATOR B Formula
30892-86-5
-
Calyxin B Formula
164991-53-1
-
kazinol B Formula
99624-27-8
-
Diazo Blue B Structure
91-91-8
-
Buxbodine B Structure
390362-51-3
-
What is Cannflavin B
76735-58-5
-
What is cyanosafracin B
96996-50-8