 Home > Encyclopedia > 1-Bromo-3-fluoro-5-nitrobenzene

1-Bromo-3-fluoro-5-nitrobenzene

1-Bromo-3-fluoro-5-nitrobenzene structure

CAS No:
7087-65-2
Formula:
C6H3BrFNO2
Chemical Name:
1-Bromo-3-fluoro-5-nitrobenzene
Synonyms:
Benzene,1-bromo-3-fluoro-5-nitro-;1-Bromo-3-fluoro-5-nitrobenzene
Categories:
Organic Chemistry > Organic Fluorine Compound

Request for Quotation

1-Bromo-3-fluoro-5-nitrobenzene Basic Attributes

Molecular Weight：

190.01

Exact Mass：

220.00

EC Number：

1533716-785-6

DSSTox ID：

DTXSID20567064

HScode：

2904909090

Characteristics

PSA：

45.8

XLogP3：

2.5

Appearance：

Yellow Liquid

Density：

1.8±0.1 g/cm3

Boiling Point：

245.5°C at 760 mmHg

Flash Point：

103.3±21.8 °C

Refractive Index：

1.580

Safety Information

Hazard category：

6.1

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

1-Bromo-3-fluoro-5-nitrobenzene Use and Manufacturing

To a solution of 2-27 (702 mg, 3 mmol) in EtOH (3 mL) at 0 °C, was added 6 ml 60percent H2S04 followed by slow addition (in portions) of NaNO2 (414 mg, 6 mmol). Upon reaction completion of the addition, the stirring was continued for lh while the temperature was kept during 0-5 °C. FeSO47H2O (4.38 g, 6 mmol) was then added and the resulting mixture was stirred for another 3h. The mixture was then concentrated, water was added and the resulting aqueous mixture was extracted with DCM (20 mL x 3). The combined organic layers were washed with brine (20 mL), dried over Na2SO4, filtered and concentrated. The resulting residue was purified by prep-TLC and eluted with DCM/MeOH = 60/1 to provide intermediate 2-28 (yellow solid, 448 mg, 68percent yield).

Computed Properties

Molecular Weight:220.00
XLogP3:2.5
Hydrogen Bond Acceptor Count:3
Exact Mass:218.93312
Monoisotopic Mass:218.93312
Topological Polar Surface Area:45.8
Heavy Atom Count:11
Complexity:161
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 1-Bromo-3-fluoro-5-nitrobenzene

LEAP CHEM CO., LTD. Contact Supplier

CN
4 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

3-Bromo-5-fluoroaniline

CAS No.: 7087-65-2

Content: 99.00%

Inquiry

23 Suppliers of 1-Bromo-3-fluoro-5-nitrobenzene

Latest News on 1-Bromo-3-fluoro-5-nitrobenzene

Learn More Other Chemicals

4-(Trifluoromethyl)benzeneacetic acid

32857-62-8
3-BROMO-2-FLUORO-6-PICOLINE

375368-78-8
2,4-Diisopropylphenol

2934-05-6
1,2-Diiodotetrafluoroethane Formula

354-65-4
6-METHYL-2-PIPERIDINECARBOXYLICACID Formula

99571-58-1
2,4-Dichloro-6-picoline Formula

42779-56-6
1-BROMO-1H,1H,2H,2H-PERFLUORODECANE Structure

21652-57-3
Perfluorohexanoic acid Structure

307-24-4
What is 6-chloro-2-naphthalenethiol

392330-26-6
What is 2,3-Dichloro-5-nitropyridine

22353-40-8

Hot Searches: 138-86-3 cas no; globalx; methane formula; magnesium phosphate formula; fluoroethylene carbonate; sds acetone

Guide of 1-Bromo-3-fluoro-5-nitrobenzene

Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
Learn More Other Chemicals

1-Bromo-3-fluoro-5-nitrobenzene

SDS

Request for Quotation



Complaint

Email:

Message:

Send Message