Chloramphenicol sodium succinate

445.19

444.010315

213-568-1

872109HX6B

DTXSID2024747

C47972

161.58000

0.90410

Chloramphenicol sodium succinate is a white powder. (NTP, 1992)

716.3ºC at 760mmHg

387ºC

H2O: soluble 50mg/mL

Celiac-rat LD50: 1400 mg/kg; Intravenous-Mouse LD50: 1530 mg/kg

Thermal decomposition releases toxic nitrogen oxides, chlorides, sodium oxide fumes

Freely soluble in water.

Alcohols and Polyols

NONH for all modes of transport

3

40

22-36

AB6905000

Xn

The warehouse is low-temperature, ventilated and dry

P280

H351

Flash point data for this chemical are not available, but it is probably combustible. (NTP, 1992)

|Warning|H351 (95%): Suspected of causing cancer [Warning Carcinogenicity]|P201, P202, P281, P308+P313, P405, and P501|Aggregated GHS information provided by 40 companies from 3 notifications to the ECHA C&L Inventory.

Fires involving this material may be controlled using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

practically nontoxic

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

SYMPTOMS: Symptoms of exposure to this compound include bone marrow depression, serious and fatal blood disorders, nausea, vomiting, glossitis and stomatitis, diarrhea, enterocolitis, headache, mild depression, mental confusion, delirium, optic and peripheral neuritis, fever, macular and vesicular rashes, angioedema, urticaria, anaphylaxis, Herxheimer reactions, and "Gray Syndrome". ACUTE/CHRONIC HAZARDS: This chemical may cause skin irritation. When heated to decomposition it emits very toxic fumes. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

chloramphenicol hemisuccinate

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients