Cyanuric chloride

184.411

184.41

203-614-9

5U4L4QHD6I

1231

3512

2670

DTXSID6026799

Crystals from ether or benzene|Colorless, monoclinic crystals from C6H6

2933691000

38.67000

2.00

Cyanuric chloride appears as a colorless crystalline solid with a pungent odor. Melting point 146°C. Density 1.32 g / cm3. Very slightly soluble in water. Toxic by ingestion and inhalation of vapors. Irritates skin and eyes. Used to make dyes.

1.32 g/cm³

146 °C

192 °C

214.4±8.8 °C

1.586

Solubility in water: reaction

Cyanuric chloride should be stored in strictly dry conditions. The solid should be stored in a cool place to avoid an increase in particle size. Tank farms for molten product must have a well-designed heat-tracing system that includes the vent and relief lines.

0.023 mm Hg at 25 deg C (est)

Relative vapour density (air = 1): 6.4

Pungent odor

Henry's Law constant = 4.9X10-7 atm cu m/mol at 25 °C (est)

CHLORINE ATOMS EASILY SUBSTITUTED WITH ALKYL, ALKOXY, ALKYLTHIO & HYDROXY GROUPS|HIGH REACTIVITY OF THREE CL ATOMS DECREASES AS SUBSTITUTION PROCEEDS|Hydroxyl radical reaction rate constant = 3.7X10-15 cu cm/molec-sec at 25 °C (est)

Reacts exothermically with water, especially if catalyzed or heated, to generate fumes of hydrochloric acid. Very slightly soluble in water.

Amines, Phosphines, and Pyridines

Water-Reactive

CYANURIC CHLORIDE reacts rapidly and exothermically with water to generate hydrogen chloride. A mixture with water in an industrial reactor with refrigeration turned off developed pressure that blew gaskets and filled the building with flammable vapors. An explosion occurred when the vapors were ignited [MCA Case History 1869(1972)]. Runaway reactions have occurred with acetone/water; methanol/water, ethoxyethanol/water, allyl alcohol/sodium hydroxide/water, 2-butanone/sodium hydroxide/water, and methanol/sodium bicarbonate [Loss Prev. Bull., 1979, (25), 21]. Reacts with methanol to give gaseous methyl chloride. Reacts rapidly with bicarbonates to generate gaseous carbon dioxide. Reacts vigorously with dimethyl formamide (DMF) to form carbon dioxide after a deceptive induction period [BCISC Quart. Safety Summ., 1960, 35, 24]. Can react with reducing agents to generate heat and products that may be gaseous (causing pressurization of closed containers). The products may themselves be capable of further reactions (such as combustion in the air).

256 kJ/kg

147.7 °C at 255 kPa

II

8

UN 2670 8/PG 2

1

R14;R22;R26;R34;R43

S26-S28-S36/37/39-S45-S46-S63-S28A

XZ1400000

C:Corrosive

Separated from food and feedstuffs. See Chemical Dangers. Dry. Well closed. Keep in a well-ventilated room.

Stable. Incompatible with strong oxidizing agents, water.

P260-P280-P284-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

H302-H314-H317-H330-H335

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Reacts violently with water producing cyanuric acid, hydrochloric acid and heat. Reacts with methanol, dimethylformamide, dimethyl sulfoxide and 2-ethoxyethanol.|Cyanuric chloride reacts vigorously and exothermically with dimethylformamide after a deceptively long induction period. The 1:1 adduct initially formed decomposes above 60 °C with evolution of carbon dioxide and formation of a dimeric unsaturated quarternary ammonium salt.|DIMETHYL SULFOXIDE DECOMPOSES VIOLENTLY ON CONTACT WITH ... CYANURIC CHLORIDE...|... ACTS AUTOCATALYTICALLY WITH WATER AT... 30 °C TO PRODUCE CYANURIC ACID, HYDROCHLORIC ACID & HEAT. AN EXPLOSION OCCURRED DURING INDUSTRIAL PROCESS IN WHICH CYANURIC CHLORIDE & WATER WERE MIXED. REFRIGERATION HAD BEEN TURNED OFF. PRESSURE BUILT UP IN REACTOR ... EXPLOSION OCCURRED WHEN VAPORS WERE IGNITED.

Organization for Economic Cooperation and Development; Screening Information Data Set for Cyanuric Chloride, CAS #108-77-0 (November 2001)|Gesellschaft Deutscher Chemiker (GDCh)/Advisory Committee on Existing Chemicals of Environmental Relevance (BUA) Cyanuric Chloride (2,4,6-trichloro-1,3,5-triazine). Verlag, Stuttgart, Germany (1995). Criteria document /concerned occupational exposure to cyanuric chloride/.

Excerpt from ERG Guide 157 [Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. For UN1796, UN1826, UN2031 at high concentrations and for UN2032, these may act as oxidizers, also consult ERG Guide 140. Vapors may accumulate in confined areas (basement, tanks, hopper/tank cars, etc.). Substance may react with water (some violently), releasing corrosive and/or toxic gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water. (ERG, 2016)|Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.|Corrosives, Reactive - 2nd degree

|Danger|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P260, P261, P264, P270, P271, P272, P280, P284, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P320, P321, P330, P333+P313, P363, P403+P233, P405, and P501|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P260, P261, P264, P270, P271, P272, P280, P284, P285, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P304+P341, P305+P351+P338, P310, P312, P320, P321, P330, P333+P313, P342+P311, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 888 companies from 17 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H301: Toxic if swallowed [Danger Acute toxicity, oral]|P201, P202, P260, P261, P264, P270, P271, P272, P280, P281, P284, P301+P310, P302+P352, P304+P340, P305+P351+P338, P307+P311, P308+P313, P310, P312, P314, P320, P321, P330, P332+P313, P333+P313, P362, P363, P403+P233, P405, and P501|P201, P202, P260, P261, P264, P270, P271, P272, P280, P281, P284, P285, P301+P312, P302+P352, P304+P340, P304+P341, P305+P351+P338, P307+P311, P308+P313, P310, P312, P314, P320, P321, P330, P332+P313, P333+P313, P342+P311, P362, P363, P403+P233, P405, and P501

Excerpt from ERG Guide 157 [Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 157 [Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. A vapor-suppressing foam may be used to reduce vapors. DO NOT GET WATER INSIDE CONTAINERS. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. Prevent entry into waterways, sewers, basements or confined areas. SMALL SPILL: Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Use clean, non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal. (ERG, 2016)

Excerpt from ERG Guide 157 [Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)]: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. (ERG, 2016)|NO WORKPLACE STANDARDS HAVE BEEN ESTABLISHED FOR CYANURIC CHLORIDE. IN VIEW OF ITS HIGHLY TOXIC NATURE BY INHALATION THIS CHEMICAL SHOULD BE HANDLED WITH GREAT CAUTION TO PREVENT INHALATION OF DUST. ... SKIN & EYE CONTACT SHOULD ALSO BE CAREFULLY AVOIDED. SINCE CYANURIC CHLORIDE IS USED ALMOST EXCLUSIVELY AS A PROCESS INTERMEDIATE IN CLOSED SYSTEMS, THE HAZARDS ARE MINIMIZED.|Local exhaust or breathing protection. Protective gloves. Protective clothing. Face shield, or eye protection in combination with breathing protection.|Personal protection: complete protective clothing including self-contained breathing apparatus.|PERSONNEL...SHOULD BE PROTECTED FROM CONTAMINATION...ESP...UNDER CONDITIONS OF HIGH HUMIDITY.

If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use dry chemical, dry sand, or carbon dioxide. Do not use water on material itself. If large quantities of combustibles are involved, use water in flooding quantities as spray and fog.

CYANURIC CHLORIDE WAS PARTIALLY (50%) HYDROLYZED TO CYANURIC ACID BY TREATMENT WITH SODIUM HYDROXIDE AT 80 °C. THE SOLN OBTAINED WAS TREATED WITH SODIUM OXYCHLORIDE AT PH 9-10 & AT 50 & 70 °C. USING 5.5 MOL OF ACTIVE CL/MOL OF CYANURIC CHLORDE, 99% OF CYANURIC CHLORIDE WAS DECOMP ACCORDING TO THE EQUATION. THE REACTION TIME AT 50 & 70 °C WERE 40 & 15 MIN.|Sweep spilled substance into sealable containers. Carefully collect remainder, then remove to safe place.|Environmental considerations - and spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete.|Environmental considerations - water spill: Use natural barriers or oil spill control booms to limit spill travel. Use natural deep water pockets, excavated lagoons, or sand bag barriers to trap material at bottom. Remove trapped material with suction hoses.

THE BASIC VENTILATION METHODS ARE LOCAL EXHAUST VENTILATION AND DILUTION OR GENERAL VENTILATION.|...SUBSTITUTION OF LESS IRRITATING SUBSTANCES...REDESIGN OF OPERATIONS...PREVENT CONTACT, PROVISION OF A PHYSICAL BARRIER AGAINST CONTACT, PROPER WASHING FACILITIES, WORK CLOTHING AND STORAGE FACILITIES, PROTECTIVE CLOTHING, AND BARRIER CREAMS. MEDICAL CONTROL...|If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers.|Personnel protection: Avoid breathing dusts, and fumes from burning material. Avoid bodily contact with the material. ... If contact with the material anticipated, wear appropriate chemical protective clothing.|SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

/GUIDE 157: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE/WATER -SENSITIVE)/ Health: TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns, or death. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat which will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.|/GUIDE 157: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE/WATER -SENSITIVE)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Vapors may accumulate in confined areas (basement, tanks, hopper/tank cars etc.). Substance will react with water (some violently), releasing corrosive and/or toxic gases. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or contaminated with water.|/GUIDE 157: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE/WATER -SENSITIVE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas.|/GUIDE 157: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE/WATER -SENSITIVE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.|For more DOT Emergency Guidelines (Complete) data for CYANURIC CHLORIDE (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

IN HUMAN VOLUNTEERS, THE 1-MIN THRESHOLD IRRITATION EFFECT OF INHALED CYANURIC CHLORIDE WAS FOUND TO BE 0.3 MG/CU M.|...HAS SEVERE IRRITANT EFFECT ON EYES & RESP PASSAGES, BUT LESS EFFECT ON SKIN.

Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations. Personal protection: complete protective clothing including self-contained breathing apparatus.

Separated from food and feedstuffs. See Chemical Dangers. Dry. Well closed. Keep in a well-ventilated room.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

The substance is severely irritating to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the vapour or fume may cause lung oedema. The effects may be delayed. Medical observation is indicated.

Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma.

AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!

Use local exhaust or breathing protection.

Protective gloves. Protective clothing.

Wear face shield or eye protection in combination with breathing protection.

This action promulgates standards of performance for equipment leaks of Volatile Organic Compounds (VOC) in the Synthetic Organic Chemical Manufacturing Industry (SOCMI). The intended effect of these standards is to require all newly constructed, modified, and reconstructed SOCMI process units to use the best demonstrated system of continuous emission reduction for equipment leaks of VOC, considering costs, non air quality health and environmental impact and energy requirements. Cyanuric chloride is produced, as an intermediate or a final product, by process units covered under this subpart.

LC50 Rat (Wistar, Han-Ibm) inhalation 86 mg/cu m (4 hr) (purity > or = 99%)|LD50 Rat (Tif: RAIf (SPF)) oral 208 mg/kg|LC50 Rat (Wistar, female) inhalation 201 mg/cu m (4 hr) (purity > or = 93.6%)|LC50 Rat (Wistar, male) inhalation 150 mg/cu m (4 hr) (purity > or = 93.6%)|For more Non-Human Toxicity Values (Complete) data for CYANURIC CHLORIDE (10 total), please visit the HSDB record page.

Cyanuric chloride's production and use as a precursor in the synthesis of herbicides and insecticides, optical brighteners, dyes, and plastics(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 120(SRC), determined from a structure estimation method(2), indicates that cyanuric chloride will have high mobility in soil(SRC). Volatilization of cyanuric chloride from moist soil surfaces(SRC) is not expected to be an important environmental fate process given an estimated Henry's Law constant of 4.9X10-7 atm-cu m/mole(SRC), derived using a fragment constant estimation method(3). Volatilization from dry soil surfaces is not expected(SRC), based on an estimated vapor pressure of 0.023 mm Hg(SRC), derived from a structure estimation method(4). Complete anaerobic degradation of 250-500 uM of cyanuric chloride solutions incorporated into a methanogenic aquifer slurry was observed after a one year time period(5); however, cyanuric chloride hydrolyzes rapidly(6) and the degradation was likely due to hydrolytic dehalogenation rather than biodegradation(SRC).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 120(SRC), determined from a structure estimation method(2), indicates that cyanuric chloride is unlikely to adsorb to suspended solids and sediment in water(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 4.9X10-7 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF value of 2(SRC), from an estimated log Kow of 1.73(6), and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). cyanuric chloride hydrolyzes rapidly in water(8). Approximately 40% degradation was observed in 1 hour at a temperature of 30 °C(8). Complete anaerobic degradation of 250-500 uM of cyanuric chloride solutions incorporated into a methanogenic aquifer slurry was observed after a one year time period(9); however, the degradation was likely due to abiotic (hydrolysis) rather than biotic (microbial) processes(SRC).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), cyanuric chloride, which has an estimated vapor pressure of 0.023 mm Hg at 25 °C(SRC), determined from a fragment constant estimation method(2), will exist solely as a vapor in the ambient atmosphere. Vapor phase cyanuric chloride is degraded slowly in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be about 4,300 days(SRC), calculated from its rate constant of 3.7X10-15 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3).

The rate constant for the vapor-phase reaction of cyanuric chloride with photochemically-produced hydroxyl radicals has been estimated as 3.7X10-15 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 4,300 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). A suspension of cyanuric chloride in ice water was stable for about 12 hours; however, at 30 °C more than 40% hydrolyzed to cyanuric acid in 1 hour(2). Cyanuric chloride does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(3).

An estimated BCF of 2 was calculated in fish for cyanuric chloride(SRC), using an estimated log Kow of 1.73(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF value suggests the potential for bioconcentration in aquatic organisms is low(SRC). Cyanuric chloride hydrolyzes rapidly in water(4), thus eliminating bioconcentration as an important environmental fate property.

Using a structure estimation method based on molecular connectivity indices(1), the Koc for cyanuric chloride is estimated as 120(SRC). According to a classification scheme(2), this estimated Koc value suggests that cyanuric chloride possesses high mobility in soil(SRC).

The Henry's Law constant for cyanuric chloride is estimated as 4.9X10-7 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This value indicates that cyanuric chloride is not expected to volatilize from water surfaces or moist soil surfaces(2). Moreover, cyanuric chloride hydrolyzes rapidly in water(3), thus eliminating volatilization as an important environmental fate property. Cyanuric chloride is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 0.023 mm Hg(SRC), determined from a fragment constant method(4).

NIOSH (NOES Survey 1981-1983) NIOSH (NOES Survey 1981-1983) has statistically estimated that 2,337 workers (299 of these are female) are potentially exposed to cyanuric chloride in the US(1). Occupational exposure may occur through dermal contact with this compound at workplaces where cyanuric chloride is produced or used(SRC).

Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other. (See all compounds classified as Cross-Linking Reagents.)

Hydrolysis caused by improper handling can result in cyanuric acid impurities

Excerpt from ERG Guide 157 [Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)]: TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Reaction with water or moist air may release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)

Excerpt from ERG Guide 157 [Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)]: Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. In case of contact with Hydrofluoric acid (UN1790), flush with large amounts of water. For skin contact, if calcium gluconate gel is available, rinse 5 minutes, then apply gel. Otherwise, continue rinsing until medical treatment is available. For eyes, flush with water or a saline solution for 15 minutes. For minor skin contact, avoid spreading material on unaffected skin. Keep victim calm and warm. Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed. (ERG, 2016)

Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist respirations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Activated charcoal is not effective ... . Do not attempt to neutralize because of exothermic reaction. Cover skin burns with dry, sterile dressings after decontamination ... . /Organic acids and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Early intubation, at the first sign of upper airway obstruction, may be necessary. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Organic acids and related compounds/

/HUMAN EXPOSURE STUDIES/ In human volunteers, the 1-min threshold irritation effect of inhaled cyanuric chloride was found to be 0.3 mg/cu m.|/SIGNS AND SYMPTOMS/ ...HAS SEVERE IRRITANT EFFECT ON EYES & RESP PASSAGES, BUT LESS EFFECT ON SKIN. SENSITIVITY & CHRONIC ECZEMA HAVE BEEN OBSERVED.|/CASE REPORTS/ Cyanuric chloride is a lachrymator and an irritant to the eyes and nose. Exposure of a laboratory assistant to a small amount of vapor resulted in rash on the neck and behind the ears with irritation.|/CASE REPORTS/ An, in general, healthy male (age 54) was exposed to cyanuric chloride during an inspection in a factory where herbicides were produced. Cyanuric chloride (one of the basic materials) was accidentally released, because a vessel got broken. The man was totally submerged under the powder. Signs of intoxication consisted of irritation of the skin, eyes and pharynx, followed by serious obstructive pulmonary syndrome with impairment of alveolar capillary exchanges. No effects on the heart function were seen (although a slightly abnormal ECG was reported from an pre-exposure investigation). The man recovered within 20 days.|/BIOMONITORING/ 39 workers with known history of long-term exposure to cyanuric chloride (between 1 and 22 years) were investigated. Investigations included anamnesis, physical examination (with special attention to lungs, skin and eyes), lung function (forced expiratory volume) and blood pressure measurements. Medical records of another 21 workers previously exposed to incidental high concentrations, who had changed jobs in the mean time, were checked. Determination of concentrations at the workplace. Samples (30-60 min) were taken during the filling procedure (worst case) and during normal production procedures (both room and personal monitoring). The samples were analyzed after adsorption tosilicagel, desorption with H2SO4, hydrolysis to cyanuric acid (70 min at 70 °C) and analysis of the cyanuric acid by HPLC with UV detection. No effects on any of the measured parameters were found. FEV was within normal ranges. Accidental acute exposure to high doses of cyanuric chloride was reported to lead to irritation/corrosion of the conjunctiva and skin irritation. After inhalation of the test substance coughing, breathing problems and shortness of breath were seen. These effects disappeared completely after a short time and did not result in persisting problems. Measured concentrations were 7.09 = or - 9.22 ug/cu m, 4.43 = or - 2.72 ug/cu m and 92.76 = or - 147.52 cu m, for filling, room and personal monitoring, respectively.

1,3,5-trichlorotriazine

The substance can be absorbed into the body by inhalation and by ingestion.

Burning sensation. Cough. Laboured breathing. Shortness of breath. Sore throat.

Redness. Pain.

Redness. Pain.

More than 70% of production is used for pesticides and especially herbicides, with about &0% of that volume for atrazine. ... Less than 30% of demand is accounted for by industrial applications, predominantly optical brighteners, UV stabilizers, reactive dyes, and certain anthraquinone dyes.

All other basic organic chemical manufacturing|1,3,5-Triazine, 2,4,6-trichloro-: ACTIVE|ACYLATION OF AMINO-AZO DYESTUFF WITH TRICHLORO-S-TRIAZINE...PRODUCES REACTIVE DYES WHICH GIVE WASH-FAST SHADES ON COTTON OR WOOL...|ASSAY FOR SERUM ANGIOTENSIN-CONVERTING ENZYME IS BASED ON COLORIMETRIC DETERMINATION OF HIPPURATE WITH CYANURIC CHLORIDE/DIOXAN REAGENT.|THE MULTIFUNCTIONAL REAGENT 1,3,5-TRICHLOROTRIAZINE YIELDED RESULTS SIMILAR TO METHYL-PARA-HYDROXYBENZIMIDATE WHEN COUPLING AMINO-HAPTENS TO THE SURFACE OF SRBC (SHEEP RED BLOOD CELLS) FOR USE IN THE HEMOLYTIC SPOT ASSAY.|Worldwide production exceeds 100,000 tons/year

FAST-SCAN DIFFERENTIAL PULSE POLAROGRAPHY USED TO DETECT CYANURIC CHLORIDE IN AIR.|CYANURCHLORIDE WAS DETECTED BY IR SPECTROSCOPY AT 1266 CM-1, WHICH GAVE A 16% RECOVERY.|Cyanuric chloride can be assayed via the melamine complex by IR spectroscopy after hydrolysis of a chloroform extract, or by titration of excess reagent after reaction with morpholine.

Fire Hazards -> Corrosives, Reactive - 2nd degree