2-Chloro-1,3-propanediol
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2-Chloro-1,3-propanediol
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CAS No:
497-04-1
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Formula:
C3H7ClO2
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Chemical Name:
2-Chloro-1,3-propanediol
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Synonyms:
1,3-Propanediol,2-chloro-;2-Chloro-1,3-propanediol;Glycerol β-chlorohydrin;2-Chloro-1,3-dihydroxypropane
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CAS No:
Description
colourless liquid
2-chloro-1,3-propanediol is a colorless liquid. (NTP, 1992)
2-chloro-1,3-propanediol is a colorless liquid. (NTP, 1992)
Characteristics
40.46000
-0.69
2-chloro-1,3-propanediol is a colorless liquid. (NTP, 1992)
1.3241 g/cm3 @ Temp: 20 °C
122.5-123.5 °C @ Press: 13.5 Torr
104.1±21.8 °C
1.474
Soluble (NTP, 1992)
Hygroscopic. Water soluble (NTP, 1992).
Alcohols and Polyols
A halogenated alcohol. Many alcohols are flammable. Polyols are generally combustible, but their generally low volatility means that they are poorly flammable. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.
Safety Information
Stable. Hygroscopic. Incompatible with strong oxidizing agents.
Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992)
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)
MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves. RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)
Drug Information
SYMPTOMS: Symptoms of exposure to this compound may include eye and nasal irritation, nausea, vomiting, giddiness, dizziness, incoordination, and coma. ACUTE/CHRONIC HAZARDS: This compound is a local skin and eye irritant. It is toxic by ingestion and inhalation and can be absorbed through the skin. When heated to decomposition it emits toxic fumes. (NTP, 1992)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Generally, the induction of vomiting is NOT recommended outside of a physician's care due to the risk of aspirating the chemical into the victim's lungs. However, if the victim is conscious and not convulsing and if medical help is not readily available, consider the risk of inducing vomiting because of the high toxicity of the chemical ingested. Ipecac syrup or salt water may be used in such an emergency. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
2-MCPD
Computed Properties
Molecular Weight:110.54
XLogP3:-1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:110.0134572
Monoisotopic Mass:110.0134572
Topological Polar Surface Area:40.5
Heavy Atom Count:6
Complexity:28
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes