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Matrine

Matrine structure

CAS No:
519-02-8
Formula:
C15H24N2O
Chemical Name:
Matrine
Synonyms:
1H,5H,10H-Dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one,dodecahydro-,(7aS,13aR,13bR,13cS)-;Matrine;Matridin-15-one;(7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one;(+)-Matrine;α-Matrine;NSC 146051;NSC 318810;Vegard;Bioca;Matrine-fluensulfone mixt.;569-23-3;21914-56-7
Categories:
Cosmetic Ingredient > Antioxidant Ingredient

Description

Matrine(Sophocarpidine; α-Matrine) is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor and u-receptor agonist.IC50 Value: 540 μg/ml (inhibit gastric cancer cell line MNK45, MTT) [1]Target: u-receptor/kappa opioid in vitro: MTT assay showed that the matrine was able to inhibit gastric cancer cell line MNK45 in a dose-dependent manner. The concentration required for 50% inhi

Matrine is an alkaloid.

Matrine Basic Attributes

Molecular Weight：

248.36400

Exact Mass：

248.36

EC Number：

610-750-6

UNII：

N390W430AC

NSC Number：

146051

DSSTox ID：

DTXSID00274188

HScode：

1302199001

Characteristics

PSA：

23.55000

XLogP3：

1.74750

Density：

1.0888 g/cm³ @ Temp: 85 °C

Melting Point：

76 °C

Boiling Point：

233 °C @ Press: 6 Torr

Flash Point：

172.7ºC

Refractive Index：

1.536

Safety Information

wgk germany：

hazard class code：

R20/21/22

safety instructions：

S22; S26; S36/37/39; S45

Marks：

Precautionary statement(s)：

P264, P270, P280, P301+P312, P305+P351+P338, P330, P337+P313, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P305+P351+P338, P330, P337+P313, and P501|Aggregated GHS information provided by 42 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

matrine

Matrine Use and Manufacturing

Antifungal, nematocide Antibacterial and anti-inflammatory drugs, used to treat chronic cervicitis, bacillary dysentery, enteritis and other diseases. Diuretic effect, anti-pathogen effect

Computed Properties

Molecular Weight:248.36
XLogP3:1.6
Hydrogen Bond Acceptor Count:2
Exact Mass:248.188863393
Monoisotopic Mass:248.188863393
Topological Polar Surface Area:23.6
Heavy Atom Count:18
Complexity:356
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 519-02-8

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China Factory Supply Matrine / SOPHOCARPIDINE / alpha-matrine CAS 519-02-8

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Trader Supplier of Ethyl 6,4-Dihydroxybenzaldehyde,tetramethylpyrazine,Spermine,Lipoic Acid,Aripiprazole,3,Edoxaban,Rutin,Tetrahydrocurcumin,Pregabalin Powder,Olopatadine Hydrochloride,β-Nicotinamide Mononucleotide,Gabapentin powder,8-dichlorooctanoate,Meloxicam,Febuxostat,(R)-3-Piperidinamine dihydrochloride,Azilsartan,Voriconazole,Magnolol,Paclitaxel Powder,Ezetimibe,Monobenzone Powder,(R)-3-(Boc-Amino)piperidine,Quercetin

radix sophorae flavescentis Matrine 98% white powder

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135 Suppliers of Matrine

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Guide of Matrine

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
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